Deoxycholic Acid (Belkyra®)
Belkyra® permanently reduces submental fullness (“double chin”) using a series of targeted injections that dissolve unwanted fat beneath the chin.

What is it?
Belkyra®—known as Kybella® in the United States—is an injectable treatment designed to permanently dissolve small, localized fat deposits under the chin. It contains deoxycholic acid, a naturally occurring molecule that helps the body break down and absorb dietary fat. When injected precisely into submental fat, it destroys the targeted fat cells, which are then metabolized and eliminated naturally by the body.
At AvenueMD, Belkyra® is performed by Dr. Jennifer Salsberg, ensuring meticulous technique and safe, natural-looking results. Treatments are customized to each patient’s anatomy, ensuring subtle refinement rather than overcorrection. The goal is to create balance and definition along the jawline while preserving the integrity of the surrounding tissue.
How does it work?
During treatment, a series of small injections are administered beneath the chin in a precise grid-like pattern. The deoxycholic acid selectively breaks down fat cell membranes, after which the body naturally clears the destroyed cells through the lymphatic system.
Each session takes approximately 20–30 minutes and requires no anesthesia, though a topical numbing agent may be applied for comfort. Swelling and tenderness are normal and typically subsides within 7-10 days. Most patients require 2–4 sessions spaced about 1-2 months apart for optimal results.
Once the fat cells are destroyed, they cannot return—making the result permanent when a stable weight is maintained.
Recovery and downtime
Downtime is minimal, though temporary swelling, firmness, or mild bruising under the chin can occur and usually resolves within several days. Some patients experience a feeling of fullness or tenderness in the area, which subsides naturally as the body processes the treated fat.
Most patients resume work and daily activities the next day, though waiting 24–48 hours before intense exercise is recommended. Visible contour improvement begins within 4–6 weeks, with continued refinement over subsequent sessions.
Frequently Asked Questions
Who is a good candidate for Belkyra®?
Belkyra® is ideal for individuals bothered by excess fullness under the chin caused by fat, rather than loose skin. It is best suited for patients seeking a non-surgical alternative to liposuction or neck lift procedures.
How many treatments will I need?
Most patients require 2–4 treatments spaced 1-2 months apart. The exact number depends on the amount of submental fat and your desired level of refinement.
Is the treatment painful?
Discomfort is minimal. A numbing cream or ice may be used before injections to reduce sensitivity. Mild swelling and tenderness afterward are normal and temporary.
When will I see results?
Initial improvement is typically visible after the second session, with final results appearing 2–3 months after the last treatment.
Are results permanent?
Yes. Once fat cells are destroyed, they cannot return. Maintaining a stable weight helps preserve long-term results.
Can Belkyra® be combined with other treatments?
Yes. Belkyra® pairs well with skin-tightening procedures such as Forma RF or Morpheus RF Microneedling to enhance definition and tone in the lower face and jawline.
